Harnessing agent-based frameworks in CellAgentChat to unravel cell–cell interactions from single-cell and spatial transcriptomics

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Figure 3.
Figure 3.

Analysis of cell communications in developing mouse hippocampus and squamous cell carcinoma (SCC) using CellAgentChat. (A) UMAP of scRNA-seq data across time points for the developing mouse data set. (B) Heat map displays inferred cell communication network at E12.5 in the developing mouse. (C) Dot plot of the top 25 LR pairs identified at E12.5 in the developing mouse. (D) Heat map displays inferred cell communication network in the SCC. (E) Dot plot of the top 25 LR pairs identified in SCC.

This Article

  1. Published in Advance May 2, 2025, doi: 10.1101/gr.279771.124 Genome Res. 35: 1646-1663

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