Accurate short-read alignment through r-index-based pangenome indexing

Table 2.

Statistics for indexing and aligning to the pan-MHC Chr 6 pangenome

Aligner Moni-align vg map vg giraffe
Total Chr 6 reads 23,996,850 ± 6941 23,996,850 ± 6941 23,996,850 ± 6941
Chr 6 aligned reads 21,864,028 ± 6234 23,831,015 ± 6605 23,996,303 ± 6931
MHC aligned reads 584,793 ± 1059 640,116 ± 751 644,751 ± 746
Index CPU time (min) 107 109 4
Index peak memory (GB) 7.36 14.68 4.85
Align CPU time (min) 16,486 ± 1936 894 ± 376 258 ± 382
Align peak memory (GB) 11.48 ± 0.73 2.25 ± 0.17 4.05 ± 0.01
  • Average and standard deviation for each category, calculated from the alignments of the five HG005 read subsamples produced by the three aligners.

This Article

  1. Genome Res. 35: 1609-1620

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