Accurate short-read alignment through r-index-based pangenome indexing

Table 1.

Statistics for indexing and aligning to GRCh38 Chr 6

Aligner Moni-align vg map vg giraffe
Total Chr 6 reads 23,996,850 ± 6941 23,996,850 ± 6941 23,996,850 ± 6941
Chr 6 aligned reads 21,735,403 ± 5668 23,830,814 ± 6628 23,996,324 ± 6927
MHC aligned reads 579,417 ± 1032 639,421 ± 774 644,479 ± 761
Index CPU time (min) 56 129 4
Index peak memory (GB) 3.93 14.31 4.69
Align CPU time (min) 1102 ± 281 795 ± 73 81 ± 17
Align peak memory (GB) 2.55 ± 0.01 2.22 ± 0.06 4.02 ± 0.01
  • Average and standard deviation for each category, calculated from the alignments of the five HG005 read subsamples produced by the three aligners.

This Article

  1. Genome Res. 35: 1609-1620

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