Highly accurate assembly polishing with DeepPolisher

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Figure 1.
Figure 1.

DeepPolisher pipeline overview. The PHARAOH pipeline leverages phase block information from ONT UL reads to correct the haplotype assignment of PacBio HiFi reads. The corrected alignment is passed to DeepPolisher, which is an encoder-only transformer model that predicts the underlying assembly sequence and proposes corrections in VCF format.

This Article

  1. Genome Res. 35: 1595-1608

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