Figure 1.
Comparison of alternative lossless compression methods. Bar chart shows compression ratios achieved when applying different lossless compression methods to a typical ONT PromethION signal data set (HG002-Prom5K Chr 22 subset) (see Supplemental Table S1). Compression ratio is calculated as follows: Uncompressed Size/Compressed Size. A wide range of alternative methods (n = 44) was tested, most of which combine multiple algorithms. Algorithms are indicated in shorthand with “_” separators on the vertical axis, and Supplemental Table S2 provides a full summary of the algorithms used.
