Charting the regulatory landscape of TP53 on transposable elements in cancer

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Figure 3.
Figure 3.

MER61 and LTR10 subfamilies are universally enriched as driver promoters. (A,B) TE subfamily enrichment profile for upregulated and downregulated DETs under either DMSO (A) or doxorubicin (DOX) treatment (B). (C,D) TE subfamily enrichment for open DARs (C) and closed DARs (D) in either DMSO or DOX treatment in HCT116. (E) Numbers of different TE-derived promoters and corresponding transcripts initiated from each TE subfamilies, colored by type of genes with which each transcript is associated.

This Article

  1. Published in Advance May 13, 2025, doi: 10.1101/gr.279398.124 Genome Res. 35: 1456-1471

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