BINDER achieves accurate identification of hierarchical TADs by comprehensively characterizing consensus TAD boundaries

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Figure 7.
Figure 7.

Contribution of hierarchical TADs in transcriptional coregulation. (A) Schematic of random genome permutation (for details, see Supplemental Methods) and up(down)-coregulated TADs. Barplot of the number of up(down)-coregulated TADs and lineplot of the corresponding Z-scores (B) and P-values (C) for each cell type in GR path.

This Article

  1. Published in Advance March 17, 2025, doi: 10.1101/gr.279647.124 Genome Res. 35: 1194-1208

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