Optical genome mapping identifies rare structural variants in neural tube defects

Table 4.

Demographic and clinicopathological findings in NTD cases and mothers

Characteristics Groups Number (n)
NTD Isolated 74
Complex 30
NTD type Anencephaly 43
Spina bifida 45
Encephalocele 6
Craniorachischisis 10
Ethnicity Caucasian 69
African American 19
Hispanic 6
Maternal age Mean ± SD (years) 26 ± 6 (range 14–41)
Maternal diabetes Yes 2
No 88
Maternal obesity Yes 10
No 79
Folic acid supplementation Yes 15
No 45
  • Information not available: Ethnicity (n = 10), maternal age (n = 3), maternal diabetes (n = 14), maternal obesity (n = 15), and folic acid supplementation (n = 44).

This Article

  1. Genome Res. 35: 798-809

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