Optimizing nanopore adaptive sampling for pneumococcal serotype surveillance in complex samples using the graph-based GNASTy algorithm

Table 2.

Alignment accuracy comparison between graph pseudoalignment in GNASTy (referred to as “graph”) and minimap2

Tool No. TP No. FN No. TN No. FP Sensitivity Specificity
Graph 1149 495 494790 3566 0.699 0.993
minimap2 713 931 497514 842 0.434 0.998

  • Sensitivity is defined as TP/(TP + FN), specificity is defined as TN/(TN + FP).

This Article

  1. Published in Advance March 4, 2025, doi: 10.1101/gr.279435.124 Genome Res. 35: 1025-1040

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