Optimizing nanopore adaptive sampling for pneumococcal serotype surveillance in complex samples using the graph-based GNASTy algorithm

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 2.
Figure 2.

Spn23F whole-genome enrichment assembly comparison. Each panel describes an Spn23F assembly generated from 0.1 Spn23F dilutions with each nontarget organism. For each panel, the top plot shows the read coverage (solid), defined as the absolute number of bases aligning to a locus, and number of small errors (≤50 bp, dashed), and the bottom plot shows aligned contigs (colors) and large errors (black bars, >50 bp) in each assembly. Loci of interest are annotated by gray bars; CBL, as well as ICESp23FST81 and ψMM1 prophage, which are missing in this isolate of Spn23F (Croucher et al. 2012).

This Article

  1. Published in Advance March 4, 2025, doi: 10.1101/gr.279435.124 Genome Res. 35: 1025-1040

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research