Joint imputation and deconvolution of gene expression across spatial transcriptomics platforms

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Figure 2.
Figure 2.

Evaluating SIID on simulated data. (A) A simulated Xenium and corresponding Visium data set with gene expression of cell types obtained from a matching scRNA-seq data set (Janesick et al. 2023). (B) R2 of imputed gene expression for holdout genes from SIID and Tangram stratified by coverage. (C) Average Jensen-Shannon (JS) divergence between ground truth and predicted cell type mixture proportions predicted by SIID, STdeconvolve, and SpiceMix for simulated Visium data over all spots stratified by coverage.

This Article

  1. Genome Res. 35: 2734-2743

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