Quadrupia provides a comprehensive catalog of G-quadruplexes across genomes from the tree of life

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 9.Figure 9.
Figure 9.

Quadrupia browse pages for reference genomes. (A) A table of species entries. By default, 20 entries per page are shown with the following columns: accession, organism, taxonomic group, and number of G4s. (B) The Quadrupia genome entry page. An example is shown for the genome of Homo sapiens (GCF_009914755.1). The page includes the name of the organism, the taxonomy ID, the taxonomic group, the assembly accession, the assembly name, the sequencing level, and the source database. In addition, for genomes with matches to experimentally validated G4 data, a section is displayed with the relevant information. (C) G4s identified using regular expressions and G4Hunter. The output is sorted by the length of the G4, and the table displays the source, chromosome/contig name, the start and end coordinates of the G4, its length, and, for G4Hunter, the G4Hunter score. The table is sortable, and the results can be downloaded. The genome page shows the top 50 largest sequences for each category, and the user has the option to explore the full set of G4s for each genome with additional annotations.

This Article

  1. Genome Res. 35: 2578-2600

Preprint Server