Figure 6.
G4 distribution patterns relative to replication origins in bacterial phyla. Results shown for Bacillota (A), Pseudomonadota (B), and Cyanobacteria (C). Enrichment of G4s in forward- and reverse-strand orientation is shown in yellow and pink, respectively. Results are shown for G4 Hunter-based and regex-based algorithms. We discretized the circular bacterial chromosomes in 1001 bins, relative to oriC, for each calculating the total number of G4 sequences divided by the total number of G4s that span the whole chromosome, to estimate the local enrichment of G4s. The average GC skew is also calculated and shown in purple.
