Tree-based differential testing using inferential uncertainty for RNA-seq

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Figure 3.
Figure 3.

Comparison of mehenDi with Terminus where mehenDi is able to find signal that is lost by Terminus groups. (A) Example of a mehenDi node that is overaggregated in Terminus for the BrSimNorm data set. (i) Subtree representing the transcripts covered by the Terminus group. (ii) Inferential replicates for the Terminus group. (iii) Inferential replicates for the selected node output by mehenDi. (B) Example of a mehenDi node that is not aggregated enough in Terminus for the BrSimNorm data set. (i) Subtree representing the transcripts covered by the mehenDi group. (ii) Inferential replicates for the Terminus group. (iii) Inferential replicates for the selected node output by mehenDi.

This Article

  1. Published in Advance August 21, 2025, doi: 10.1101/gr.279981.124 Genome Res. 35: 2326-2338

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