Figure 2.
Examples of domain segmentation using ESM2-RecCut. The cartoon visualizations (by PyMOL) of the protein structures are shown on the left, with predicted domains (by ESM2-RecCut) shown in different colors: the first domain in green and the second domain in red. The figures in the middle show ESM-2 contact maps of the two proteins. In the first example, RecCut performed on ESM-2 predicted contact maps is able to accurately recover the SCOP annotated domain regions (two domains). In the second example, RecCut resulted in two subdomains, as compared to a single domain defined in SCOP.
