Stefan Schrod; Niklas Lück; Robert Lohmayer; Stefan Solbrig; Dennis Völkl; Tina Wipfler; Katherine H. Shutta; Marouen Ben Guebila; Andreas Schäfer; Tim Beißbarth; Helena U. Zacharias; Peter J. Oefner; John Quackenbush; Michael Altenbuchinger

Spatial Cellular Networks from omics data with SpaCeNet

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Figure 3.

Spatial interactions improve on goodness of fit. The figures show absolute prediction residuals for spatially associated genes Mbp (top row) and Flt1 (bottom row) in the mouse visual cortex data from Wang et al. (2018) with respect to their position in space. The left column (A,D) shows the absolute residuals between the ground truth data and the predictions based on the intracellular model parameters only, $\text{[math]}$ . The middle column (B,E) displays the residuals if both intra- and intercellular interactions are considered, $\text{[math]}$ . The right column (C,F) shows the contributions from spatial interactions only, $\text{[math]}$ .