Scalable summary-statistics-based heritability estimation method with individual genotype level accuracy

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Figure 1.
Figure 1.

Comparison of SNP heritability estimates across methods. SUM-RHE heritability estimates are comparable to those from RHE or BOLT-REML/GCTA-GREML and are significantly more accurate than those of LDSC and SumHer. Because of computational limitations, BOLT-REML/GCTA-GREML was not run on the N = 50k simulations. Dashed hatches denote individual-level data methods.

This Article

  1. Published in Advance July 22, 2024, doi: 10.1101/gr.279207.124 Genome Res. 34: 1286-1293

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