Benchmarking bulk and single-cell variant-calling approaches on Chromium scRNA-seq and scATAC-seq libraries

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Figure 5.
Figure 5.

SBS 96 trinucleotide mutation breakdown for common ground-truth, scATAC-RP, and scRNA-RP variants as seen in EPSRC1 (A), which is representative of the group trend, and the SBS1536 breakdown of scRNA-RP variants in exonic regions only (B), demonstrating that the signature is maintained in exonic regions and is characterized by repeat extensions of all base patterns. Images were generated using the SigProfiler suite.

This Article

  1. Published in Advance August 15, 2024, doi: 10.1101/gr.277066.122 Genome Res. 34: 1196-1210

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