A fast and adaptive detection framework for genome-wide chromatin loop mapping from Hi-C data

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Figure 5.
Figure 5.

Fast adaptation of YOLOOP on multiple species and proximity ligation protocols. (A) YOLOOP is able to accurately capture loop anchors under multiple experimental protocols (ChIA-PET, HiChIP, Micro-C) in human and mouse cells. (B) Sparsity distribution for contact maps from various experiment protocols. (C) Statistical recovery rate and precision benchmarking YOLOOP against existing algorithms on Hi-C, ChIA-PET, and HiChIP GM12878 contact maps. (D) Enumeration of YOLOOP's predictions on contact maps from multiple protocols.

This Article

  1. Published in Advance August 13, 2024, doi: 10.1101/gr.279274.124 Genome Res. 34: 1174-1184

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