Genome-wide relaxation of selection and the evolution of the island syndrome in Orkney voles

Table 2.

The 10 most significantly enriched GO biological process terms of genes that experienced hard sweeps only in the Orkney vole population

Term ID Term name Padj Term size Intersection size
GO:0006955 Immune response 5.07 × 10−11 1794 17
GO:0048002 Antigen processing and presentation of peptide antigen 5.17 × 10−8 71 6
GO:0002478 Antigen processing and presentation of exogenous peptide antigen 7.13 × 10−8 30 5
GO:0042832 Defense response to protozoan 1.18 × 10−7 33 5
GO:0001562 Response to protozoan 1.88 × 10−7 36 5
GO:0019884 Antigen processing and presentation of exogenous antigen 2.17 × 10−7 37 5
GO:0019882 Antigen processing and presentation 9.88 × 10−7 115 6
GO:0019886 Antigen processing and presentation of exogenous peptide antigen via MHC class II 2.03 × 10−6 18 4
GO:0002495 Antigen processing and presentation of peptide antigen via MHC class II 4.85 × 10−6 22 4
GO:0002504 Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 7.03 × 10−6 24 4
  • Padj refers to P-value of enrichment adjusted with the g:SCS method for multiple testing correction. Term size refers to the number of genes in the GO term. Intersection size refers to the number of genes under hard sweep. All the GO terms listed are immune related.

This Article

  1. Genome Res. 34: 851-862

Preprint Server