Table 1.
6mA statistics in WT and ΔAMT1 cells
| Single molecule | WT | ΔAMT1 | ||
|---|---|---|---|---|
| Number | Percentage (%) | Number | Percentage (%) | |
| ApT | 992,618,784 | 100 | 842,024,326 | 100 |
| 6mApT sites | 18,750,787 | 1.89 | 4,248,723 | 0.50 |
| Full | 8,373,723 | 89.32 | 64,270 | 3.03 |
| Hemi-W | 998,137 | 5.32 | 2,051,797 | 48.29 |
| Hemi-C | 1,005,304 | 5.36 | 2,068,386 | 48.68 |
| Total 6mApT | 18,750,787 | 100 | 4,248,723 | 100 |
-
(Top) The number of total ApT (with or without modification) and 6mApT sites in DNA molecules fully mapped to the MAC. Both W and C are counted. Percentage of DNA methylation is also calculated [6mApT/(total ApT)]. (Bottom) The number of full-6mApT and hemi-6mApT duplexes. Note that each full-6mApT duplex contains two 6mA sites, whereas each hemi-6mApT duplex only contains one site. Percentages of full-6mApT and hemi-6mApT duplexes are also calculated.
