A new framework for exploratory network mediator analysis in omics data

Table 1.

Top 10 GO biological processes in the subgraph identified by medNet on the METABRIC data set

GOBPID P-value Term
GO:0051169 0.0004 Nuclear transport
GO:0009895 0.0004 Negative regulation of the catabolic process
GO:0043467 0.0005 Regulation of generation of precursor metabolites and energy
GO:0010628 0.0006 Positive regulation of gene expression
GO:0007265 0.0008 RAS protein signal transduction
GO:0007346 0.0008 Regulation of mitotic cell cycle
GO:0010507 0.0011 Negative regulation of autophagy
GO:0060341 0.0014 Regulation of cellular localization
GO:0071900 0.0015 Regulation of protein serine/threonine kinase activity
GO:0008219 0.0018 Cell death

This Article

  1. Genome Res. 34: 642-654

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