Phased nanopore assembly with Shasta and modular graph phasing with GFAse

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Figure 6.
Figure 6.

Diagram of sampling method for optimizing proximity linkages in an assembly graph. Edge weights in the contact graph are represented by teal curves. For each inner iteration, a greedily converged phase state is used to update a distribution of orientations among bubbles. Bubbles with the strongest signal at the end of sampling are merged for successive iterations. By the end of each round r of merging, the largest possible bubble set is 2 ^ r in size.

This Article

  1. Genome Res. 34: 454-468

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