Phased nanopore assembly with Shasta and modular graph phasing with GFAse

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Figure 3.
Figure 3.

Phasing metrics for HG002 assemblies, as evaluated using the GIAB v4.2.1 benchmark VCF, phased with Strand-seq using WhatsHap (see Methods). All Shasta assemblies are unpolished. Assemblies not phased with GFAse are shaded gray. Each dot represents a chromosome error rate, generated by WhatsHap compare. Native Hifiasm Hi-C uses 30× coverage. Each pair of Hi-C is ∼17×. Pore-C flow cells have ∼30× yield.

This Article

  1. Genome Res. 34: 454-468

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