Translation-dependent and -independent mRNA decay occur through mutually exclusive pathways defined by ribosome density during T cell activation

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Figure 6.
Figure 6.

Relationship between GC content in the coding sequence, TDD, and TID. (A) Codon stability coefficient computed for each codon using the TDDindex (CSC(TDD)) in resting (left, green bars) and activated (right, violet bars) T CD4+ cells. Codons colored in red correspond to AU3 codons, and codons colored in blue correspond to GC3. (B) Same as A but using the TIDindex (CSC(TID)) instead of the TDDindex.

This Article

  1. Published in Advance March 20, 2024, doi: 10.1101/gr.277863.123 Genome Res. 34: 394-409

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