Preferential formation of Z-RNA over intercalated motifs in long noncoding RNA

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Figure 4.
Figure 4.

TDS of C-rich (predicted iM) lncRNA oligos show pH-dependent Z-RNA secondary structure formation. TDS showing normalized difference in absorbance from 220–330 nm between unfolded (90°C) and folded (20°C) conditions in 10 mM sodium cacodylate buffer at pH 5.5 (A), pH 6.0 (B), and pH 7.0 (C). Tel26 (dashed line) shows positive control DNA iM.

This Article

  1. Published in Advance February 14, 2024, doi: 10.1101/gr.278236.123 Genome Res. 34: 217-230

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