Hydra has mammal-like mutation rates facilitating fast adaptation despite its nonaging phenotype

Table 2.

SNV calling in nine-animal pedigree

Individuals Youngest budded 2018 Middle budded 2012 Oldest budded 2006 Mother
Age (years) 0.08 0.08 7.20 7.30 8.10 11.10 12.00 12.30 12.60
# Raw reads 193.91 151.63 290.73 304.89 302.57 281.69 301.31 304.27 191.77
# Mapped reads (million)a 146.97 114.18 199.57 209.62 206.60 191.17 200.59 217.67 143.28
% Mapped readsa 80.08 79.76 72.02 71.98 71.65 70.96 69.52 74.63 79.03
Mother versus buds (2006–2018)
# Downsampled reads (million) 141.19 141.18 141.18 141.19 141.17 141.18 141.18 141.18 -
# Covered basesb 442.90 444.13 440.64 436.60 446.12 444.74 442.49 444.50 -
% Genome coveredb 0.52 0.52 0.52 0.51 0.52 0.52 0.52 0.52 -
# Combined variants 98 113 86 89 111 107 96 109 -
Individuals versus reference (≪1973 until last sexual reproduction)
# Covered bases (million)b 654.78 673.32 475.15 567.36 669.09 684.24 665.69 678.00 564.77
% Genome coveredb 76.69 78.86 55.65 66.45 78.37 80.14 77.97 79.41 66.15
# Variants (million) 4.60 4.69 3.38 3.98 4.67 5.21 4.64 4.71 4.75
# Variants in CDS (million) 0.18 0.18 0.14 0.16 0.18 0.18 0.18 0.18 0.16
  • aUniquely mapping reads after removal of duplicates.

  • b(Coverage ≥10).

This Article

  1. Genome Res. 34: 2217-2228

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