Table 2.
Tissues that are significantly enriched for genes associated with the change in carnivory score
| Tissue | Enrichment statistic | Parametric P-value | Parametric Q-value | Permulation P-value | Permulation Q-value |
|---|---|---|---|---|---|
| Tibial artery | 0.111 | 2.64 × 10−4 | 0.002 | 6.30 × 10−4 | 0.032 |
| Liver | −0.158 | 1.28 × 10−19 | 6.38 × 10−18 | 0.002 | 0.037 |
| Kidney cortex | −0.146 | 7.42 × 10−7 | 1.24 × 10−5 | 0.002 | 0.037 |
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Permulation P-values represent the proportion of 100,000 permulations that produced a stronger enrichment test statistic than the observed value for each gene set. Multiple hypothesis testing corrections were performed by generating Q-values using Storey's correction method (Storey et al. 2020) (FDR = 0.05). A negative enrichment statistic signifies the following pattern: the greater the decrease in carnivory, the higher the rate of evolution of the gene.
