Construction and evaluation of a new rat reference genome assembly, GRCr8, from long reads and long-range scaffolding

Table 5.

Comparison of the location of 16 human Chr X and Chr Y pseudoautosomal region (PAR) genes with the corresponding mouse and rat genes

Gene Hsa RefSeq Hsa position Mmu RefSeq Mmu position Rn Seq Rn position
PLCXD1 NM_018390 Chr X: 109,617–131,584
Chr Y: 108,952–130,733
NM_207279.3 Chr 5: 110,247,661–110,253,819 XM_006249594.4 Chr 12: 52,238,611–52,241,876
GTPBP6 NM_012227 Chr X: 132,978–149,874
Chr Y: 132,127–148,960
NM_145147.5 Chr 5: 110,251,843–110,256,063 NM_001135840.1 Chr 12: 52,234,612–52,238,574
PPP2R3B NM_013239 Chr X: 165,039–218,172
Chr Y: 168,543–224,805
Absent NM_001139492.1 Chr 14: 103,483–110,740
SHOX NM_001191546 Chr X: 471,065–484,646
Chr Y: 484,200–497,713
NM_001302357.1 Chr 3: 66,879,056–66,889,104 Absent
CRLF2 NM_022148 Chr X: 1,035,704–1,058,464
Chr Y: 1,050,450–1,072,677
NM_001310694.1 Chr 5: 109,702,575–109,706,859 NM_134465.2 Chr 14: 118,930–123,637
CSF2RA NM_001161531 Chr X: 1,116,112–1,155,181
Chr Y: 1,129,402–1,169,666
NM_009970.2 Chr 19: 61,212,840–61,216,856 NM_001037660.1 Chr 14: 113,073–118,247
IL3RA NM_002183 Chr X: 1,187,106–1,226,335
Chr Y: 1,201,550–1,246,463
NM_008369.2 Chr 14: 8,114,270–8,123,357 NM_139260.3 Chr 12: 21,431,846–21,437,547
SLC25A6 NM_214418 Chr X: 1,229,803–1,235,689
Chr Y: 1,250,365–1,255,930
Absent XM_039097301.1 Chr 18: 70,846,358–70,847,597
ASMTL NM_004192 Chr X: 1,246,707–1,294,817
Chr Y: 1,266,964–1,315,887
Absent NM_001105915.2 Chr 12: 21,429,098–21,431,849
P2RY8 NM_178129 Chr X: 1,304,499–1,338,509
Chr Y: 1,325,953–1,401,516
Absent Absent
AKAP17A NM_005088 Chr X: 1,393,022–1,403,887
Chr Y: 1,455,997–1,466,652
NM_001418372.1 Chr X: 169,098,201–169,105,547 NM_001127246.2 Chr 12: 21,424,191–21,428,933
ASMT NM_001171038 Chr X: 1,416,353–1,441,907
Chr Y: 1,478,823–1,502,882
NM_001308488.2 Chr X: 169,106,356–169,111,844 NM_144759.2 Chr 12: 21,418,488,–21,423,338
DHRSX NM_145177 Chr X: 1,829,953–2,113,734
Chr Y: 1,894,168–2,177,723
NM_001033326 Chr 4: 156,390,377–156,410,432 NM_001105914.1 Chr 12: 21,413,533–21,418,321
ZBED1 NM_004729 Chr X: 2,099,191–2,113,734
Chr Y: 2,163,179–2,177,723
Absent Absent
CD99 NM_002414 Chr X: 2,304,268–2,354,297
Chr Y: 1,050,450–1,072,677
NM_138309.3 Chr X: 70,463,666–70,536,455 NM_001100804.1 Chr 20: 56,000,484–56,005,135
XG NM_001141919 Chr X: 2,365,041–2,429,263
Chr Y: absent
Absent Absent
  • The genes identified are all assigned to the human (Hsa) PAR, and most are present in both the X and Y Hsa PAR. In the mouse (Mmu), six of these genes are absent from the genome assembly (GRCm39), seven are on autosomes, and three are located on Chr X. In the GRCr8 assembly, four genes are absent from the assembly, whereas 12 are located on autosomes. Human data are from T2T assembly CHM 13v2.0. Mouse data are from GRCm39. Rat data are from BN-HiFi using annotation transfer from mRatBN7.2 (Liftoff).

This Article

  1. Genome Res. 34: 2081-2093

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