Accurate bacterial outbreak tracing with Oxford Nanopore sequencing and reduction of methylation-induced errors

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Figure 4.
Figure 4.

MPOA workflow to mask ambiguous and low coverage (0×–10× sequencing depth) positions in genome files. The workflow provides masked assemblies containing all contigs and separate masked chromosomes and plasmid FASTA files. A FASTA file per sample is also generated for each ambiguous position plus surrounding bases for further analysis (Supplemental Code 2; https://github.com/replikation/MPOA).

This Article

  1. Published in Advance October 23, 2024, doi: 10.1101/gr.278848.123 Genome Res. 34: 2039-2047

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