Long-read Ribo-STAMP simultaneously measures transcription and translation with isoform resolution

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Figure 4.
Figure 4.

LR-Ribo-STAMP can profile changes in translation at the gene level for cells in disease state. (A) SUnSET assay and global quantification of LR-Ribo-STAMP EditsC at the gene level for normoxia (NT) and hypoxia (CoCl2) treatment conditions. (B) Gene Ontology analyses of genes having higher (left) and lower (right) LR-Ribo-STAMP EditsC following hypoxia. (C) LR-Ribo-STAMP EditsC and RPKM of EIF4E and EIF4E2 in normoxia and hypoxia. (D) LR-Ribo-STAMP EditsC and gene expression of CISD1. Significance: (***) P ≤ 0.001, (**) P ≤ 0.01, (*) P ≤ 0.05.

This Article

  1. Published in Advance June 21, 2024, doi: 10.1101/gr.279176.124 Genome Res. 34: 2012-2024

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