m6A detection on SQK-RNA004 data set. (A) ROC and PR curve of Xron on SQK-RNA004 data against Dorado. Results of m6Anet and MINES from SQK-RNA002 data on the same HEK293T cell line are also plotted for comparison. (B) Comparison of ROC and PR curves for Xron and Dorado on 2070 dense sites where neighboring modification sites exist within five bases. (C) Venn diagram showing the overlapping sites predicted by Xron and other methods on the HEK293T cell line. (D) Coordinate distribution of the m6A methylated sites predicted by five methods against the background distribution of all DRACH sites. Only sites with at least 20 coverage were chosen. (E) Clustering plot showing the modification of the TSR3 (ENSG00000007520) mRNA transcript over 780 reads. A modification is called if the predicted probability is >0.9 and is marked with a green dot.
