Figure 1.
The HLA-DRB haplotype groups. In total, five major region configurations are defined in humans, containing functional genes (indicated in blue) and pseudogenes (indicated in gray). The DRA locus is illustrated as well (white box). All configurations contain a DRB1 and a DRB9 entity. The haplotype groups contain one or two functional genes. The nomenclature of the haplotype groups follows their association with different serotypes. Figure is adapted from Doxiadis et al. (2008a).
