Table 1.
Samples of the Summary page from the PWAS Hub (phenotypes are partitioned by sex)
| ICD-10 | Disease/phenotype | Sex | # of cases | # of controls | # of PWAS sig. genes | Prevalence (%) | Ratio F:M |
|---|---|---|---|---|---|---|---|
| E03 | Other hypothyroidism | M | 2566 | 123,075 | 9 | 2.04 | |
| F | 11,121 | 138,062 | 63 | 7.45 | |||
| Both | 13,687 | 261,137 | 77 | 4.98 | 3.65 | ||
| I10 | Essential (primary) hypertension | M | 40,358 | 85,283 | 2 | 32.12 | |
| F | 33,732 | 115,451 | 22 | 22.61 | |||
| Both | 74,090 | 200,734 | 70 | 26.96 | 0.70 | ||
| R31 | Unspecified hematuria | M | 8075 | 117,566 | 8 | 6.43 | |
| F | 5694 | 143,489 | 26 | 3.82 | |||
| Both | 13,769 | 261,055 | 37 | 5.01 | 0.59 | ||
| I25 | Chronic ischemic heart disease | M | 17,853 | 107,788 | 19 | 14.21 | |
| F | 6963 | 142,220 | 0 | 4.67 | |||
| Both | 24,816 | 250,008 | 15 | 9.03 | 0.33 | ||
| E780 | Pure hypercholesterolemia | M | 19,586 | 106,055 | 16 | 15.59 | |
| F | 12,490 | 136,693 | 6 | 8.37 | |||
| Both | 32,076 | 242,748 | 27 | 11.67 | 0.54 | ||
| E11 | Type 2 diabetes mellitus | M | 11,098 | 114,543 | 12 | 8.83 | |
| F | 6791 | 142,392 | 3 | 4.55 | |||
| Both | 17,889 | 256,935 | 38 | 6.51 | 0.52 |
