Figure 1.
An interconnected chromatin tapestry. Illustration depicting the interwoven nature of chromatin features that create a balance necessary for proper neural differentiation and development. Some examples of the individual threads of this chromatin tapestry include (A) chromatin accessibility, (B) DNA methylation, (C) 3D chromatin compartments, and (D) other long-range chromatin interactions. Because of their relationship, disruption of one feature likely ripples throughout the others, which may explain multiple correlated epigenetic aspects of aberrant neural development.
