Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

H3K4me3 distribution differs between IGN and embryo. (A) Pearson's correlation plot for IGN (horizontal) versus embryo (vertical) for each histone modification. (B) Overlap of genes marked by H3K4me3 in IGN versus embryos. Significance assessed by hypergeometric distribution. (C) Transcript abundance in IGN for IGN-specific, embryo-specific, and shared genes. P-value legend: (*) <0.05, (**) <0.005, (***) <0.0005, (****) <0.0005. (D) Breadth of H3K4me3 peaks in embryos (left) and IGN (right). (E) Metagene plots of H3K4me3 signal (as normalized IP/input ratio) around genes marked by H3K4me3 in IGN and embryo.

This Article

  1. Published in Advance December 26, 2023, doi: 10.1101/gr.278247.123 Genome Res. 34: 57-69

Preprint Server



Current Issue

  1. January 2026, 36 (1)
  1. Current Issue
  1. Alert me to new issues of Genome Research