Table 3.
Number of variants detected in Mutyh−/− tumors using WES
| Tumor ID | Total | ||||
|---|---|---|---|---|---|
| RY1114 T6 | RY1114 T7 | RY1115 T2 | RY1115 T6 | ||
| Transition | |||||
| G:C > A:T | 34 | 29 | 26 | 12 | 101 |
| A:T > G:C | 21 | 23 | 12 | 5 | 61 |
| Transversion | |||||
| G:C > T:A | 272 | 172 | 297 | 123 | 864 |
| G:C > C:G | 3 | 4 | 3 | 4 | 14 |
| A:T > T:A | 6 | 9 | 2 | 3 | 20 |
| A:T > C:G | 3 | 5 | 2 | 3 | 13 |
| SNV total | 339 | 242 | 342 | 150 | 1073 |
| Indel, MNS | 5 | 9 | 2 | 8 | 23 |
| Total | 344 | 251 | 344 | 157 | 1096 |
-
(MNS) Multinucleotide substitution.
