Figure 5.
New extremities without canonical subtelomeric elements. (A) Scheme of the loss of 4.9 kb of sequence and formation of a new telomere at subtelomere 14L of tel-m2-1. The new junction sequence is shown. (B) Scheme of the complex new 3L extremity in tel-m1-0 and tel-m1-1. The sequencing depth for Chromosome 7 is shown, revealing the duplicated 500-kb region in tel-m1-1. The sequences of Junction A, B, and C are shown in Supplemental Figure S7, A through C. (C) Scheme of the Robertsonian fission that occurred on Chromosome 7 of tel-m2-1. The new centromere-proximal extremities were stabilized by telomere sequences, with in addition a Sultan array and an ITS for the 7R long arm.
