Molecular processes enriched among gene deletions that increase A3B-induced mutagenesis. (A) Gene Ontology (GO) analysis for molecular processes that are enriched among gene deletions that increase A3B-induced mutation. Only categories with strengths equal to or greater than one and having at least three genes represented in the category are shown. Categories for similar processes are represented with the specific GO process with the lowest FDR-corrected P-value. (B) Functional association network for proteins that limit A3B-induced mutation as created by STRINGdb. The 61 gene deletion strains that were confirmed to increase A3B-induced mutagenesis were used in creating the network, with highest-confidence linkage settings and k-means clustering with eight nodes. Proteins without connections to other proteins in the network are hidden. Each k-means clustering node is indicated by a unique color. (C) Gene deletions that elevate A3B-induced mutation function in multiple GO processes. The specific enriched GO processes that each gene contributes to are indicated in green.
