Genetic features and genomic targets of human KRAB-zinc finger proteins

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Figure 4.
Figure 4.

Profiling of the human KZFPs. Pie chart of the data on all 378 protein-coding KZFPs. “No overexpression” indicates the number of KZFPs where the codon-optimized construct did not yield sufficient protein. “No transcript” represents KZFPs with no annotated transcript containing both the KRAB and zinc finger domains simultaneously. “No DNA synthesis” indicates the number of KZFP CDSs that could not be synthesized, with a minimum of two tries. “de Tribolet-Hardy et al. 2023” refers to the present work.

This Article

  1. Published in Advance September 20, 2023, doi: 10.1101/gr.277722.123 Genome Res. 33: 1409-1423

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