
Divergent RNA profiles in thylacine skin and skeletal muscle samples. Number of RNA sequences mapped to the 20 most abundant thylacine miRNA genes profiled in skeletal muscle (A) and skin tissue (B). (C) UMAP embedding depicting diverse tissue samples clustering belonging to dog (circular shape), Tasmanian devil (triangular shape), and opossum (inverted triangular shape) miRNA expression profiles (N = 119) available at MirGeneDB2.1 (Fromm et al. 2022), as well as miRNA profiles of thylacine skeletal muscle and skin tissues (diamond shape). (D) UMAP embedding depicting diverse tissue samples clustering belonging to sheep (circular shape) and Tasmanian devil (triangular shape) protein-coding (PC) mRNA expression profiles (N = 261 mRNAs), as well as PC mRNA expression profiles of thylacine skeletal muscle and skin tissues (diamond shape).











