Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models

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Figure 1.
Figure 1.

Overview of Sgootr. Sgootr leverages single-cell methylation sequencing data from tumor samples, incorporating copy number information when available, to jointly infer a single-cell tumor lineage tree and identify CpG sites that may harbor lineage-informative methylation changes.

This Article

  1. Genome Res. 33: 1089-1100

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