Variation in histone configurations correlates with gene expression across nine inbred strains of mice

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 6.
Figure 6.

Association of DNA methylation with gene expression (A) across genes in hepatocytes, (B) across inbred strains, and (C) in the DO population. The dark gray line shows the estimated effect of percentage of DNA methylation on gene expression. The x-axis is normalized position along the gene body running from the TSS to the TES, marked with vertical gray dotted lines. The horizontal solid black line indicates an association of zero. The shaded gray area shows a 95% confidence interval around the model fit.

This Article

  1. Genome Res. 33: 857-871

Preprint Server