Figure 5.
Mutation rate and sequence context. (A) Relative mutation rates for the 32 different classes of trinucleotides. (B) Model predictions for effects of flanking bases. (C) Estimates of model coefficients for effects of flanking bases. βb is the effect of focal C:G relative to A:T; β5 is the effect of flanking 5′ C:G relative to A:T; β3 is the effect of flanking 3′ C:G relative to A:T; BI5 is the interaction effect of 5′ C:G when the focal base is C:G; and BI3 is the interaction effect of 3′ C:G when the focal base is C:G. Range shows a 95% HPD interval of the relative mutation rate.
