Figure 4.
Box sequence conservation, snoRNA stability, and host gene expression level govern the snoRNA expression status. (A) Distribution of the predictive rank of each input feature across all selected models and iterations. (B) Frequency logos of the observed C (top panel) and D (bottom panel) motifs in expressed and nonexpressed C/D box snoRNAs (where R is a purine). The cumulative Shannon entropy (sum of the entropy per nucleotide) is shown for each logo, as well as the proportion of snoRNAs in which a motif could be found.
