Continuity of the cy0333 MCM full genomic MHC region versus three publicly available macaque reference genomes. The cy0333 MHC region (OP204634) is shown in the top panel; a cynomolgus macaque reference genome Macaca_fascicularis_5.0 (GCF_000364345) assembled from the Illumina short-read data is shown in the second panel down; the rhesus macaque reference genome Mmul_10 (GCF_003339765) assembled from the ∼13.5-kb PacBio RSII data is shown in the third panel down; and a cynomolgus macaque reference genome MFA1912RKSv2 (GCF_012559485) assembled from the ∼12-kb PacBio Sequel II data is shown in the bottom panel. Annotations for all protein-coding genes plus a subset of nonclassical MHC-I and MHC-II pseudogenes are shown for each sequence. Protein-coding genes are shown in black font, and pseudogenes are shown in gray font. All sequences are uniformly scaled, and the position in megabases for all sequences is shown across the top. Gray tracks represent the sequence for each reference, and white gaps within the gray tracks represent gaps in the assembly. The class I A region is highlighted in yellow; the class I B region is highlighted in orange, the class III region is highlighted in blue; and the class II region is highlighted in green. Gene annotations for Macaca_fascicularis_5.0, Mmul_10, and MFA1912RKSv2 are sourced from and named consistent with NCBI, and gene sizes correspond to the longest predicted translation per gene; some of these predicted translations (particularly the exceptionally long black bars present on some of the references) require further validation and refinement.
