LRCAGE proteome identifies epigenetic drug-induced TE antigens in H1299. (A) Newly characterized TE transcripts as a function of epigenetic treatment annotated with TE class at 5′ end. (B) Number of noncanonical antigens as a function of epigenetic treatment in H1299 cells annotated with antigen type. (C) MS1 intensity of antigens in H1299 cells. (D) Browser view of LTR12 transcripts encoding a drug-induced TE antigen, KEQTPDTPSL. A TSS is marked with a yellow bar, and a protein-coding region is marked with a pink bar. Newly characterized transcripts encoding a noncanonical antigen are marked with a red asterisk (*). (E) Expression level of TE loci encoding drug-induced TE antigens.
