Using long-read CAGE sequencing to profile cryptic-promoter-derived transcripts and their contribution to the immunopeptidome

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Figure 3.
Figure 3.

TE subfamilies enriched with cryptic TSSs have lower mappability scores and are evolutionarily younger than other TE subfamilies. (A) Proportion of TEs overlapping cryptic TSSs by TE class. (B) Cryptic TSS enrichment heatmap by TE class and TE subfamily. Enriched TE subfamilies were defined as having 1.5 or more enrichment scores, 100 or more total TE elements, and five or more TE elements overlapping cryptic TSSs. (C) Mappability scores of TE subfamilies by enrichment status with cryptic TSSs. (D) Evolutionary ages of TE subfamilies by enrichment status with cryptic TSSs. (C,D) Enriched indicates 11 TE subfamilies; others, 1075 TE subfamilies.

This Article

  1. Genome Res. 33: 2143-2155

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