Cohesin and CTCF do not assemble TADs in Xenopus sperm and male pronuclei

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Figure 6.
Figure 6.

The genome organization of human and frog sperm differs from that of somatic cells. (A) Contact frequency as a function of genomic distance for human sperm enriched by DGC, human IMR-90 cells by Rao et al. (2014), frog sperm enriched by DGC, and frog XL-177 cells. (B) Contact frequency as a function of genomic distance for human HeLa cells in G1 that were mock-depleted or joint-WAPL/PDS5A/PDS5B-depleted and for HeLa cells in prometaphase, all from Wutz et al. (2017).

This Article

  1. Published in Advance December 21, 2023, doi: 10.1101/gr.277865.123 Genome Res. 33: 2094-2107

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