Figure 4.
Open chromatin regions are enriched in cis-regulatory variants. Enrichment of variants mapping to NMF component-specific ATAC-seq peaks in credible sets (r2 ≥ 0.9 with the lead variant) of 3857 blood-specific and 2212 liver-specific cis eQTL, evaluated by following the method of Trynka et al. (2015). The x-axis shows statistical significance (log(1/p)) of the enrichment; y-axis, NMF component. Green indicates proximal peaks; red, distal peaks. (A) Blood-specific eQTLs. (B) Liver-specific eQTLs.
